What (who) is G syndrome - definition

SYNDROME CHARACTERIZED BY ACUTE BRAIN DAMAGE AND LIVER FUNCTION PROBLEMS

Reyes Syndrome; Reye Syndrome; Reye's Syndrome; Reyes syndrome; Reye’s Syndrome; Reye hepatocerebral syndrome; Rye syndrome; Reye s syndrome; Reye's s syndrome; Reye's syndrome; Reye’s syndrome

Opitz G/BBB syndrome

A MONOGENIC DISEASE THAT IS CHARACTERIZED BY HYPERTELORISM, HYPOSPADIAS, AND ADDITIONAL MIDLINE DEFECTS RESULTING FROM MUTATIONS TO THE MID1 GENE IN THE X-LINKED FORM OR FROM A DELETION ON CHROMOSOME 22Q11.2 IN THE AUTOSOMAL DOMINANT FORM.

Opitz G/BBB Syndrome

Opitz G/BBB syndrome, also known as Opitz syndrome, G syndrome or BBB syndrome, is a rare genetic disorder that will affect physical structures along the midline of the body.Chen, J.

https://en.wikipedia.org/wiki/Opitz_G/BBB_syndrome

Reye's syndrome

['re?z, 'r??z]

¦ noun a life-threatening metabolic disorder in young children, of uncertain cause.

Origin

1960s: named after the Australian paediatrician Ralph D. K. Reye.

Down's syndrome

CHROMOSOMAL CONDITION CHARACTERIZED BY FLAT-LOOKING FACIAL FEATURES AND WEAK MUSCLE TONE (HYPOTONIA) IN INFANCY AND IS CAUSED BY TRISOMY OF ALL OR A CRITICAL PORTION OF CHROMOSOME 21 AND IS ASSOCIATED WITH INTELLECTUAL DISABILITY

Trisomy 21; Down's syndrome; Down's Syndrome; Downs syndrome; Down Syndrome; Downs Syndrome; Síndrome de Down; Down’s Syndrome; Down-syndrome; 47,XY,+21; 47,XX,+21; History of Down syndrome; Health aspects of Down syndrome; Trisomy-21; Down's; Trisomy 21 syndrome; History of down syndrome; Sindrome de Down; Downsyndrome; Mosaic Down Syndrome; Downs' Syndrome; Downs' syndrome; DS (genetic disorder); Downes syndrome; Downes' syndrome; Downe's syndrome; Downes's syndrome; Downs's syndrome; Downe Sydrome; Mongolianism; Trisectomy 21; 21 trisomy syndrome

Note: in AM, usually use 'Down syndrome'

Down's syndrome is a disorder that some people are born with. People who have Down's syndrome have a flat forehead and sloping eyes and lower than average intelligence.

N-UNCOUNT

Wikipedia

Reye syndrome

Reye syndrome is a rapidly worsening brain disease. Symptoms of Reye syndrome may include vomiting, personality changes, confusion, seizures, and loss of consciousness. While liver toxicity typically occurs in the syndrome, jaundice usually does not. Death occurs in 20–40% of those affected with Reye syndrome, and about a third of those who survive are left with a significant degree of brain damage.

The cause of Reye syndrome is unknown. It usually begins shortly after recovery from a viral infection, such as influenza or chickenpox. About 90% of cases in children are associated with aspirin (salicylate) use. Inborn errors of metabolism are also a risk factor. The syndrome is associated with changes on blood tests such as a high blood ammonia level, low blood sugar level, and prolonged prothrombin time. Often, the liver is enlarged in the syndrome.

Prevention is typically by avoiding the use of aspirin in children. When aspirin was withdrawn for use in children in the US and UK in the 1980s, a decrease of more than 90% in rates of Reye syndrome was seen. Early diagnosis of the syndrome improves outcomes. Treatment is supportive; mannitol may be used to help with the brain swelling.

The first detailed description of Reye syndrome was in 1963 by Australian pathologist Douglas Reye. The syndrome most commonly affects children. It affects fewer than one in a million children a year. The general recommendation to use aspirin in children was withdrawn because of Reye syndrome, with use only recommended in Kawasaki disease.

https://en.wikipedia.org/wiki/Reye syndrome